Protein Purification
Apexbio Technology LLC Potent inhibitor of PARP-1 and PARP-2 912444-00-9. MFCD16661059
Potent inhibitor of PARP-1 and PARP-2 912444-00-9. MFCD16661059
American Research Products Inc Mouse Plasma protease C1 inhib
Mouse Plasma protease C1 inhibitor (SERPING1) ELISA kit from CUSABIO Detection Range 5 6 ng/mL-360 ng/mL Sensitivity 1 4 ng/mL Sample serum plasma tissue homogenates Method Sandwich
Cayman Chemical JZL 195 InHBTr asy REGE 20nmol
JZL 195 inhibitor assay reagent has been formulated and tested to work with Cayman’s Assay Kits. Detailed instructions for its use are contained in the respective Cayman Assay Kit booklet.
Abcam AG 490, JAK2/3 inhibitor, 10MG
MW 294.3 Da, Purity >99%. JAK2/3 inhibitor (IC₅₀ values are ~10 and 25 μM, respectively). Inhibits downstream activation of STAT5a/b. Effects synaptic plasticity and cytokine-independent cell growth in vitro and spatial learning, memory and tumor cell invasion in vivo.
The product is subject to the following: Abcam Restricted Use Statement
Abcam WHI-P131 hydrochloride, JAK3 inhibitor, 10MG
MW 297.31 Da, Purity >98%. Cell-permeable Janus kinase 3 (JAK3) inhibitor (IC₅₀ values of 9.1 μM and 78 μM for human and mouse recombinant proteins respectively). Selective versus JAK1, JAK2, SYK, BTK and LYN tyrosine kinases.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Tetrabenazine, VMAT2 inhibitor, 25MG
MW 317.42 g/mol. Potent, reversible VMAT2 inhibitor (IC₅₀ = 3.2 nM, Ki = 100 nM). Depletes monoamines stores and decreases uptake into synaptic vesicles. Shows antihyperkinetic effects in vivo. Orally active.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical nutrophIl Elasts InhIbItr 25mg
An N-benzoylindazole derivative that selectively targets the binding domain of neutrophil elastase (IC50 = 7 nM)
Selleck Chemical LLC Ralimetinib dimesylate 5mg 862507-23-1 LY2228820 dimesylate
Ralimetinib (LY2228820) dimesylate is a novel and potent inhibitor of p38 MAPK with IC50 of 7 nM in a cell-free assay, does not alter p38 MAPK activation. Phase 1/2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC 1-(5-isoquinolinesulfonyl)-2-methylpiperazine dihydrochloride | 108930-17-2 | MFCD00036961 | 99.6% | 364.29 g/mol | C14H19Cl2N3O2S | 5 MG
Protein kinase inhibitor H-7 dihydrochloride is a small-molecule serine/threonine kinase inhibitor commonly used to inhibit protein kinase C and related kinases in biochemical and cell-based assays. It is supplied as a solid with high reported purity for research applications.
- Potent protein kinase C (PKC) inhibitor.
- Broad-spectrum serine/threonine kinase inhibition.
- Cell-permeable and reversible inhibitor.
- High reported purity suitable for analytical and biological studies.
- Stable solid formulation for convenient storage and handling.
- Recommended storage sealed, away from moisture and light.
Cayman Chemical K-Ras G12C InhIbItr 9 1mg
An irreversible, allosteric inhibitor of the K-Ras(G12C) mutant that causes 100% modification of the protein when used at 10 µM for 24 hours in vitro
Abcam Serine Protease Assay Kit (FAM-Spacer-Leu-CMK), 25 Tests
These Serine Protease Assay Kits enable researchers to detect intracellular chymotrypsin-like serine protease activity in vitro without lysing the cell.
The product is subject to the following: Abcam Restricted Use Statement
Cayman Chemical GlutamInase InhIbItr comp 25mg
A cell-permeable, reversible inhibitor of a mitochondrial glutaminase splice variant, glutaminase C (IC50 = ~2.5 µM), which is commonly found in cancer cells; blocks transformation induced by Rho GTPases and inhibits the proliferation of cancer cell lines without affecting normal cells
Cayman Chemical VEGFR2 KInase InhIbItr II 5mg
A reversible, cell-permeable inhibitor of VEGFR2’s kinase activity (IC50 = 70 nM); less potently inhibits PDGFRβ (IC50 = 920 nM); blocks the growth of human umbilical vein endothelial cells stimulated with either VEGF or PDGF (IC50s = 110 nM and 2 µM, respectively)
Cayman Chemical Syk InhIbItr II 500ug
A cell-permeable, selective, and reversible inhibitor of Syk (IC50 = 41 nM); prevents FcεRI-mediated 5-HT release in RBL-2H3 cells in vitro (IC50 = 460 nM) and inhibits passive cutaneous anaphylaxis reactions in mice (ID50 = 13.2 mg/kg, s.c.)